Pfizer due to Lipitor patient expiry in 2010 had a projected loss of sales of 7.8 billion dollars, Takeda a potential loss in 2011 of 3.1 billion dollars due to Actos expiration, Astra Zeneca 5.9 billion dollars in 2011 due to Nexium and all other Big Pharma has a major blockbuster expiration in the period between 2010 and 2012. IMS is stating that the Patent Cliff will has an effect on total sales on between 2010 and 2012 exceeding 80 billion dollars.
